Complex Behaviour of Bile Salts at Various Temperatures Under the Influence of Antidepressant Drug (Imipramine) in Aqueous Solution

Shweta Singh; Santosh K. Sar; Tonmoy Ray

doi:doi:10.11648/j.si.20160405.13

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Complex Behaviour of Bile Salts at Various Temperatures Under the Influence of Antidepressant Drug (Imipramine) in Aqueous Solution

Shweta Singh, Santosh K. Sar, Tonmoy Ray

Published in Science Innovation (Volume 4, Issue 5)

Received: 23 September 2016 Accepted: 6 October 2016 Published: 7 November 2016

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Abstract

The present method was based on the effect of bile salt (Sodium cholate and Sodium deoxy cholate) on the dissolution of Antidepressant drug like Imipramine. Sodium cholate and Sodium deoxycholate is a type of anionic surfactants form mixed micelle with Imipramine and influence its rate of dissolution. The micellization behavior of binary anionic bile salt surfactant mixtures was investigated by conductivity method and various thermodynamical parameters are calculated. The results of the study have been analyzed by using Clint’s, Rubingh’s, and Motomura’s theories for mixed binary systems.

Published in	Science Innovation (Volume 4, Issue 5)
DOI	10.11648/j.si.20160405.13
Page(s)	235-241
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2016. Published by Science Publishing Group

Keywords

Antideprassant Drug, Sodium Cholate, Sodium Deoxycholate, Conductometer, Critical Micelle Concentration, Counter Ion Dissociation

References

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APA Style

Shweta Singh, Santosh K. Sar, Tonmoy Ray. (2016). Complex Behaviour of Bile Salts at Various Temperatures Under the Influence of Antidepressant Drug (Imipramine) in Aqueous Solution. Science Innovation, 4(5), 235-241. https://doi.org/10.11648/j.si.20160405.13

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ACS Style

Shweta Singh; Santosh K. Sar; Tonmoy Ray. Complex Behaviour of Bile Salts at Various Temperatures Under the Influence of Antidepressant Drug (Imipramine) in Aqueous Solution. Sci. Innov. 2016, 4(5), 235-241. doi: 10.11648/j.si.20160405.13

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AMA Style

Shweta Singh, Santosh K. Sar, Tonmoy Ray. Complex Behaviour of Bile Salts at Various Temperatures Under the Influence of Antidepressant Drug (Imipramine) in Aqueous Solution. Sci Innov. 2016;4(5):235-241. doi: 10.11648/j.si.20160405.13

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@article{10.11648/j.si.20160405.13,
  author = {Shweta Singh and Santosh K. Sar and Tonmoy Ray},
  title = {Complex Behaviour of Bile Salts at Various Temperatures Under the Influence of Antidepressant Drug (Imipramine) in Aqueous Solution},
  journal = {Science Innovation},
  volume = {4},
  number = {5},
  pages = {235-241},
  doi = {10.11648/j.si.20160405.13},
  url = {https://doi.org/10.11648/j.si.20160405.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.si.20160405.13},
  abstract = {The present method was based on the effect of bile salt (Sodium cholate and Sodium deoxy cholate) on the dissolution of Antidepressant drug like Imipramine. Sodium cholate and Sodium deoxycholate is a type of anionic surfactants form mixed micelle with Imipramine and influence its rate of dissolution. The micellization behavior of binary anionic bile salt surfactant mixtures was investigated by conductivity method and various thermodynamical parameters are calculated. The results of the study have been analyzed by using Clint’s, Rubingh’s, and Motomura’s theories for mixed binary systems.},
 year = {2016}
}

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TY  - JOUR
T1  - Complex Behaviour of Bile Salts at Various Temperatures Under the Influence of Antidepressant Drug (Imipramine) in Aqueous Solution
AU  - Shweta Singh
AU  - Santosh K. Sar
AU  - Tonmoy Ray
Y1  - 2016/11/07
PY  - 2016
N1  - https://doi.org/10.11648/j.si.20160405.13
DO  - 10.11648/j.si.20160405.13
T2  - Science Innovation
JF  - Science Innovation
JO  - Science Innovation
SP  - 235
EP  - 241
PB  - Science Publishing Group
SN  - 2328-787X
UR  - https://doi.org/10.11648/j.si.20160405.13
AB  - The present method was based on the effect of bile salt (Sodium cholate and Sodium deoxy cholate) on the dissolution of Antidepressant drug like Imipramine. Sodium cholate and Sodium deoxycholate is a type of anionic surfactants form mixed micelle with Imipramine and influence its rate of dissolution. The micellization behavior of binary anionic bile salt surfactant mixtures was investigated by conductivity method and various thermodynamical parameters are calculated. The results of the study have been analyzed by using Clint’s, Rubingh’s, and Motomura’s theories for mixed binary systems.
VL  - 4
IS  - 5
ER  -

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Author Information

Shweta Singh

Department of Applied Chemistry, Bhilai Institute of Technology, Durg, (C. G.) India
Santosh K. Sar

Department of Applied Chemistry, Bhilai Institute of Technology, Durg, (C. G.) India
Tonmoy Ray

Department of Biotechnology, National Institute of Technology, Durgapur, (W. B.) India

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APA Style

Shweta Singh, Santosh K. Sar, Tonmoy Ray. (2016). Complex Behaviour of Bile Salts at Various Temperatures Under the Influence of Antidepressant Drug (Imipramine) in Aqueous Solution. Science Innovation, 4(5), 235-241. https://doi.org/10.11648/j.si.20160405.13

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ACS Style

Shweta Singh; Santosh K. Sar; Tonmoy Ray. Complex Behaviour of Bile Salts at Various Temperatures Under the Influence of Antidepressant Drug (Imipramine) in Aqueous Solution. Sci. Innov. 2016, 4(5), 235-241. doi: 10.11648/j.si.20160405.13

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AMA Style

Shweta Singh, Santosh K. Sar, Tonmoy Ray. Complex Behaviour of Bile Salts at Various Temperatures Under the Influence of Antidepressant Drug (Imipramine) in Aqueous Solution. Sci Innov. 2016;4(5):235-241. doi: 10.11648/j.si.20160405.13

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@article{10.11648/j.si.20160405.13,
  author = {Shweta Singh and Santosh K. Sar and Tonmoy Ray},
  title = {Complex Behaviour of Bile Salts at Various Temperatures Under the Influence of Antidepressant Drug (Imipramine) in Aqueous Solution},
  journal = {Science Innovation},
  volume = {4},
  number = {5},
  pages = {235-241},
  doi = {10.11648/j.si.20160405.13},
  url = {https://doi.org/10.11648/j.si.20160405.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.si.20160405.13},
  abstract = {The present method was based on the effect of bile salt (Sodium cholate and Sodium deoxy cholate) on the dissolution of Antidepressant drug like Imipramine. Sodium cholate and Sodium deoxycholate is a type of anionic surfactants form mixed micelle with Imipramine and influence its rate of dissolution. The micellization behavior of binary anionic bile salt surfactant mixtures was investigated by conductivity method and various thermodynamical parameters are calculated. The results of the study have been analyzed by using Clint’s, Rubingh’s, and Motomura’s theories for mixed binary systems.},
 year = {2016}
}

Copy | Download

TY  - JOUR
T1  - Complex Behaviour of Bile Salts at Various Temperatures Under the Influence of Antidepressant Drug (Imipramine) in Aqueous Solution
AU  - Shweta Singh
AU  - Santosh K. Sar
AU  - Tonmoy Ray
Y1  - 2016/11/07
PY  - 2016
N1  - https://doi.org/10.11648/j.si.20160405.13
DO  - 10.11648/j.si.20160405.13
T2  - Science Innovation
JF  - Science Innovation
JO  - Science Innovation
SP  - 235
EP  - 241
PB  - Science Publishing Group
SN  - 2328-787X
UR  - https://doi.org/10.11648/j.si.20160405.13
AB  - The present method was based on the effect of bile salt (Sodium cholate and Sodium deoxy cholate) on the dissolution of Antidepressant drug like Imipramine. Sodium cholate and Sodium deoxycholate is a type of anionic surfactants form mixed micelle with Imipramine and influence its rate of dissolution. The micellization behavior of binary anionic bile salt surfactant mixtures was investigated by conductivity method and various thermodynamical parameters are calculated. The results of the study have been analyzed by using Clint’s, Rubingh’s, and Motomura’s theories for mixed binary systems.
VL  - 4
IS  - 5
ER  -

Copy | Download