The incidence of spina bifida (SB) is known to differ among regions. Very little has been reported about the relationship between the incidence of SB and ethnic patterns of origin in Zambia except for the general impression that it is prevalent. The aim of the study was to establish the ethnic pattern of origin of children with SB in Zambia. It was a retrospective cross sectional study. Using a checklist, data was collected from clinical files of children with SB from the University Teaching Hospital (UTH) and Beit Cure Hospital (BCH) from 2001-2010. Descriptive statistical analysis was done in SPSS version 17. A total of 253 children with SB were identified of whom 88 (35%) of them originally came from the Southern Province of the country while the lowest province was the North-Western Province with 7 (3%). Further, a total of 77 (30%) children were referred from the Southern Province of the country and the lowest province that was represented was the North-Western Province with 5 (2%). Observed is the evidence that SB is very prevalent in the Southern Province of the country. With the presence of Uranium in the Southern Province of Zambia, a serious study ought to be done to investigate the possible link of the pollutant with the prevalence of SB in the region. It is essential that the government looks seriously at Uranium Mines being operated in the Province.
Published in | Science Journal of Public Health (Volume 3, Issue 6) |
DOI | 10.11648/j.sjph.20150306.19 |
Page(s) | 852-856 |
Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
Copyright |
Copyright © The Author(s), 2015. Published by Science Publishing Group |
Ethnic Patterns, Spina Bifida, Management, Southern Province, Uranium Deposits
[1] | Adzick NS (2010). Foetal myelomeningocele: Natural history, pathophysiology and in-utero intervention. Seminars in Foetal & Neonatal Medicine, 15, 9–14. |
[2] | Kashimba Rogath Saika, Mpembeni Rose, Mghamba M Janneth, David Goodman, Diana Valencia (2015). Birth prevalence of selected external structural birth defects at four hospitals in Dar es Salaam, Tanzania, 2011–2012. Journal of Global Health, 5: 2 (1-6). |
[3] | Sukhani S, Patel YK, Chintu C (1977). Major congenital malformations in neonates at U.T.H. Lusaka Zambia. Med J Zambia, 11(5): 127-38. |
[4] | Mattison RD (2010). Environmental Exposures and Development. Curr Opin Pediatr. 22(2): 208–218. |
[5] | Al-Sabbak MS, Sadik AO, Savabi G, Savabi S, Dastgiri M. Savabieasfahani (2012). Metal Contamination and the Epidemic of Congenital Birth Defects in Iraqi Cities. Bull Environ Contam Toxicol 89: 937–944. |
[6] | Landrigan P, Kimmel C, Correa A, Eskenazi B et al (2004). Children’s health and the environment: public health issues and challenges for risk assessment. Environ Health Perspect 112(2): 257–265. |
[7] | Bocskay K, Tang D, Orjuela M, Liu X, Warburton D, Perera F et al (2005). Chromosomal aberrations in cord blood are associated with prenatal exposure to carcinogenic polycyclic aromatic hydrocarbons. Cancer Epidemiol Biomarkers Prev 14(2): 506–511. |
[8] | Ahern M, Hendryx M, Conley J, Fedorko E, Ducatman A, Zullig K et al (2011). The association between mountaintop mining and birth defects among live births in central Appalachia, 1996–2003. Environ Res 111(6): 838–846. |
[9] | Wu J, Zhang C Pei L, Chen G, & Zheng X (2014). Association between risk of birth defects occurring level and arsenic concentrations in soils of Lvliang, Shanxi province of China. Environ Pollut. 191: 1-7. |
[10] | Technical Report, Republic of Zambia (2012). The Dibwe East Project, Southern Province, Republic of Zambia. National Instrument 43-101 Technical Report. |
[11] | Lusambo V (2011). Local Geology of Dibwe East Prospect (Dibwe Mutanga Corridor). Internal report for Denison Mines Zambia Limited. |
[12] | Mitchell LE, Adzick NS, Melchionne J, Pasquariello PS, Sutton LN and Whitehead AS (2004). Spina bifida. Lancet, 364, 1885–1895. |
[13] | Buccimazza SS, Molteno CD, Dunne TT, et al. (1994). Prevalence of neural tube defects in Cape Town. Teratology 50: 194-199. |
[14] | Hendricks T, Francis N, Fyodorov D, Deneris ES (1999). The ETS domain factor Pet-1 is an early and precise marker of central serotonin neurons and interacts with a conserved element in serotonergic genes. J. Neurosci 19: 10348–10356. |
[15] | Djientcheu VP, Njamnshib AK, Wonkamc A, Njikid J, Guemsed M, Mbuf R, Obamae, AT, Kagod I, Tetayeh E and Tietched F (2008). Management of neural tube defects in a Sub-Saharan African country: The situation in Yaounde, Cameroon. Journal of Nursing Science, 275 (1), 29-32. |
[16] | Oduro H (2008). Enrichment of foods with folate: its impact on the prevalence of genetic associated diseases in African countries as compared to western countries. (http://departments.agri.huji.ac.il/external). |
[17] | Margaron FC, Poenaru D, Bransford R and Albright LA (2010). Timing of ventriculoperitoneal Shunt insertion following spina bifida closure in Kenya. Child’s Nervous System, 26, (11), 1523-1528. |
[18] | Mehdizadeh M, Roohi A, Hemami M and Esfahani S (2010). Is There any Association between Spina Bifida Occulta and Primary Vesicoureteral Reflux? Iran Journal of Pediatric, 20 (3), 348-352. |
[19] | Champbell KS, Vander L and Palisano R (2006). Physical Therapy for Children. W.B. Saunders Company: Philadelphia. |
[20] | Airede KI (1992). Neural tube defects in the middle belt of Nigeria. Journal of Tropical Pediatrics, 38, 27-30. |
[21] | Shehu BB, Ameh EA and Ismail NJ (2000). Spina bifida cystic: selective management in Zaria, Nigeria. Annals of Tropical Paediatrics 20 (3), 239-42. |
[22] | Volpe J (2001). Neural tube formation and prosencephalic development. In: Volpe J(ed) Neurology of the new born. WB Sanders: Philadelphia. |
[23] | Idowu OE and Apemiye RA (2008). Outcome of myelomeningocele repair in sub-Saharan Africa: the Nigerian experience. Acta Neurochir (Wien), 159, 911-913. |
[24] | Botto LD, Moore CA, Khoury MJ and Erickson JD (1999). Neural-tube defects. New England Journal of Medicine, 341, 1509–1519. |
[25] | Lungu MM (2001). Epidemiological characteristics of patients with myelomeningocele presenting to University Teaching Hospital – Lusaka. Master’s Degree Thesis, University of Zambia. |
[26] | Anyanwu Lofty-John Chukwuemeka, Danborno Barnabas, Hamman Wilson Oliver (2015). The Prevalence of Neural Tube Defects in Live Born Neonates in Kano, North-western Nigeria. Sub-Saharan African Journal of Medicine /Vol 2/Issue 3: 105-109. |
[27] | Swartz D Michael, Yi Cai1, Wenyaw Chan, Elaine Symanski, Laura E Mitchell, Heather E Danysh, Peter H Langlois and Philip J Lupo (2015). Air toxics and birth defects: a Bayesian hierarchical approach to evaluate multiple pollutants and spina bifida. Environmental Health, 14:16. |
[28] | Li Z, Ren A, Zhang L, Ye R, Li S, Zheng J, Hong S, Wang T and Li L (2006). Extremely high prevalence of neural tube defects in a 4-county area in Shanxi Province, China. Birth defects research. Part A. Clinical and Molecular Teratology, 74(4), 237–40. |
APA Style
Margaret M. Mweshi, Seyi Ladele Amosun, Mary P. Shilalukey-Ngoma, Esther Munalula-Nkandu. (2015). Ethnic Pattern of Origin of Children with Spina Bifida Managed at the University Teaching Hospital and Beit Cure Hospital, Lusaka, Zambia 2001-2010. Science Journal of Public Health, 3(6), 852-856. https://doi.org/10.11648/j.sjph.20150306.19
ACS Style
Margaret M. Mweshi; Seyi Ladele Amosun; Mary P. Shilalukey-Ngoma; Esther Munalula-Nkandu. Ethnic Pattern of Origin of Children with Spina Bifida Managed at the University Teaching Hospital and Beit Cure Hospital, Lusaka, Zambia 2001-2010. Sci. J. Public Health 2015, 3(6), 852-856. doi: 10.11648/j.sjph.20150306.19
AMA Style
Margaret M. Mweshi, Seyi Ladele Amosun, Mary P. Shilalukey-Ngoma, Esther Munalula-Nkandu. Ethnic Pattern of Origin of Children with Spina Bifida Managed at the University Teaching Hospital and Beit Cure Hospital, Lusaka, Zambia 2001-2010. Sci J Public Health. 2015;3(6):852-856. doi: 10.11648/j.sjph.20150306.19
@article{10.11648/j.sjph.20150306.19, author = {Margaret M. Mweshi and Seyi Ladele Amosun and Mary P. Shilalukey-Ngoma and Esther Munalula-Nkandu}, title = {Ethnic Pattern of Origin of Children with Spina Bifida Managed at the University Teaching Hospital and Beit Cure Hospital, Lusaka, Zambia 2001-2010}, journal = {Science Journal of Public Health}, volume = {3}, number = {6}, pages = {852-856}, doi = {10.11648/j.sjph.20150306.19}, url = {https://doi.org/10.11648/j.sjph.20150306.19}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjph.20150306.19}, abstract = {The incidence of spina bifida (SB) is known to differ among regions. Very little has been reported about the relationship between the incidence of SB and ethnic patterns of origin in Zambia except for the general impression that it is prevalent. The aim of the study was to establish the ethnic pattern of origin of children with SB in Zambia. It was a retrospective cross sectional study. Using a checklist, data was collected from clinical files of children with SB from the University Teaching Hospital (UTH) and Beit Cure Hospital (BCH) from 2001-2010. Descriptive statistical analysis was done in SPSS version 17. A total of 253 children with SB were identified of whom 88 (35%) of them originally came from the Southern Province of the country while the lowest province was the North-Western Province with 7 (3%). Further, a total of 77 (30%) children were referred from the Southern Province of the country and the lowest province that was represented was the North-Western Province with 5 (2%). Observed is the evidence that SB is very prevalent in the Southern Province of the country. With the presence of Uranium in the Southern Province of Zambia, a serious study ought to be done to investigate the possible link of the pollutant with the prevalence of SB in the region. It is essential that the government looks seriously at Uranium Mines being operated in the Province.}, year = {2015} }
TY - JOUR T1 - Ethnic Pattern of Origin of Children with Spina Bifida Managed at the University Teaching Hospital and Beit Cure Hospital, Lusaka, Zambia 2001-2010 AU - Margaret M. Mweshi AU - Seyi Ladele Amosun AU - Mary P. Shilalukey-Ngoma AU - Esther Munalula-Nkandu Y1 - 2015/11/17 PY - 2015 N1 - https://doi.org/10.11648/j.sjph.20150306.19 DO - 10.11648/j.sjph.20150306.19 T2 - Science Journal of Public Health JF - Science Journal of Public Health JO - Science Journal of Public Health SP - 852 EP - 856 PB - Science Publishing Group SN - 2328-7950 UR - https://doi.org/10.11648/j.sjph.20150306.19 AB - The incidence of spina bifida (SB) is known to differ among regions. Very little has been reported about the relationship between the incidence of SB and ethnic patterns of origin in Zambia except for the general impression that it is prevalent. The aim of the study was to establish the ethnic pattern of origin of children with SB in Zambia. It was a retrospective cross sectional study. Using a checklist, data was collected from clinical files of children with SB from the University Teaching Hospital (UTH) and Beit Cure Hospital (BCH) from 2001-2010. Descriptive statistical analysis was done in SPSS version 17. A total of 253 children with SB were identified of whom 88 (35%) of them originally came from the Southern Province of the country while the lowest province was the North-Western Province with 7 (3%). Further, a total of 77 (30%) children were referred from the Southern Province of the country and the lowest province that was represented was the North-Western Province with 5 (2%). Observed is the evidence that SB is very prevalent in the Southern Province of the country. With the presence of Uranium in the Southern Province of Zambia, a serious study ought to be done to investigate the possible link of the pollutant with the prevalence of SB in the region. It is essential that the government looks seriously at Uranium Mines being operated in the Province. VL - 3 IS - 6 ER -