Ghrelin is a peptide hormone made up of 28 amino acid residues; the N-terminal serine 3 residues is modified by octanoic acid, a medium-chain fatty acid. Ghrelin is mainly secreted by the stomach and has various effects, including growth hormone release, hyperphagia, lipid accumulation, suppression of insulin secretion, and hypotensive effects. Most of these physiological effects are indispensable functions for the maintenance of homeostasis and contribute to the onset and promotion of metabolic syndrome. Accordingly, it is important to combine etiological and pathological understanding based on the biochemistry and physiology of ghrelin, which has a characteristic structure. In this manuscript, after presenting biochemical information on ghrelin, we provide an outline of its physiological function.
| Published in |
American Journal of Life Sciences (Volume 3, Issue 3-2)
This article belongs to the Special Issue Biology and Medicine of Peptide and Steroid Hormones |
| DOI | 10.11648/j.ajls.s.2015030302.13 |
| Page(s) | 8-16 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
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Copyright © The Author(s), 2015. Published by Science Publishing Group |
Ghrelin, Ghrelin-O-Acyltransferase, Appetite
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APA Style
Takahiro Sato, Kanae Oishi, Takanori Ida, Masayasu Kojima. (2015). Physiological Functions and Pathology of Ghrelin. American Journal of Life Sciences, 3(3-2), 8-16. https://doi.org/10.11648/j.ajls.s.2015030302.13
ACS Style
Takahiro Sato; Kanae Oishi; Takanori Ida; Masayasu Kojima. Physiological Functions and Pathology of Ghrelin. Am. J. Life Sci. 2015, 3(3-2), 8-16. doi: 10.11648/j.ajls.s.2015030302.13
AMA Style
Takahiro Sato, Kanae Oishi, Takanori Ida, Masayasu Kojima. Physiological Functions and Pathology of Ghrelin. Am J Life Sci. 2015;3(3-2):8-16. doi: 10.11648/j.ajls.s.2015030302.13
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Download@article{10.11648/j.ajls.s.2015030302.13,
author = {Takahiro Sato and Kanae Oishi and Takanori Ida and Masayasu Kojima},
title = {Physiological Functions and Pathology of Ghrelin},
journal = {American Journal of Life Sciences},
volume = {3},
number = {3-2},
pages = {8-16},
doi = {10.11648/j.ajls.s.2015030302.13},
url = {https://doi.org/10.11648/j.ajls.s.2015030302.13},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajls.s.2015030302.13},
abstract = {Ghrelin is a peptide hormone made up of 28 amino acid residues; the N-terminal serine 3 residues is modified by octanoic acid, a medium-chain fatty acid. Ghrelin is mainly secreted by the stomach and has various effects, including growth hormone release, hyperphagia, lipid accumulation, suppression of insulin secretion, and hypotensive effects. Most of these physiological effects are indispensable functions for the maintenance of homeostasis and contribute to the onset and promotion of metabolic syndrome. Accordingly, it is important to combine etiological and pathological understanding based on the biochemistry and physiology of ghrelin, which has a characteristic structure. In this manuscript, after presenting biochemical information on ghrelin, we provide an outline of its physiological function.},
year = {2015}
}
TY - JOUR T1 - Physiological Functions and Pathology of Ghrelin AU - Takahiro Sato AU - Kanae Oishi AU - Takanori Ida AU - Masayasu Kojima Y1 - 2015/05/06 PY - 2015 N1 - https://doi.org/10.11648/j.ajls.s.2015030302.13 DO - 10.11648/j.ajls.s.2015030302.13 T2 - American Journal of Life Sciences JF - American Journal of Life Sciences JO - American Journal of Life Sciences SP - 8 EP - 16 PB - Science Publishing Group SN - 2328-5737 UR - https://doi.org/10.11648/j.ajls.s.2015030302.13 AB - Ghrelin is a peptide hormone made up of 28 amino acid residues; the N-terminal serine 3 residues is modified by octanoic acid, a medium-chain fatty acid. Ghrelin is mainly secreted by the stomach and has various effects, including growth hormone release, hyperphagia, lipid accumulation, suppression of insulin secretion, and hypotensive effects. Most of these physiological effects are indispensable functions for the maintenance of homeostasis and contribute to the onset and promotion of metabolic syndrome. Accordingly, it is important to combine etiological and pathological understanding based on the biochemistry and physiology of ghrelin, which has a characteristic structure. In this manuscript, after presenting biochemical information on ghrelin, we provide an outline of its physiological function. VL - 3 IS - 3-2 ER -
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